Stiffness of the Skin and Joints in Relation to Carpal Tunnel Syndrome
The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve. The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a...
Brief Summary
Official Title: “Correlation of Joint Stiffness and Stiffness of the Skin and the Prevelation of Carpal Tunnel Syndrome (CTS)”
The exact etiology of CTS remains yet unknown. A rise in carpal tunnel pressure is well documented, but why this phenomenon occurs is yet unknown in most patients. There is an absolute or relative narrowing of the carpal tunnel, which results in a compression of the median nerve.
The investigators postulate, that a stiffer flexor retinaculum (roof of carpal tunnel) will be less compliant. As a consequence of this stiffer retinaculum the pressure in the carpal tunnel will rise more quickly in stiff patients resulting in CTS-complaints.
A relation between connective tissue composition and joint stiffness is proven. This relationship possibly extends to a relation between stiffness of the skin, joint stiffness and the prevalence of CTS.
- Study Type: Observational
- Study Design: Observational Model: Case Control, Time Perspective: Cross-Sectional
- Study Primary Completion Date: November 2010
Arms, Groups and Cohorts in this Clinical Trial
- : Carpal tunnel syndrome
- Patients with carpal tunnel syndrome
- : Trigger finger
- Patients with trigger fingers
- : Dupuytren Contracture
- Patients with Dupuytren
- : Trauma to the hand
- Patients with an acute trauma to the hand
Outcome Measures for this Clinical Trial
Primary Measures
- Joint stiffness
- Time Frame: In the 1st month
Safety Issue?: No
- Time Frame: In the 1st month
- Stiffness of the skin
- Time Frame: in the 1st month
Safety Issue?: No
- Time Frame: in the 1st month
Secondary Measures
- Physical activities
- Time Frame: In the 1st month
Safety Issue?: No
- Time Frame: In the 1st month
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Caucasian
- Carpal tunnel release OR Trigger finger OR Dupuytren OR an acute trauma to the hand
Exclusion Criteria:
- Hypo-/hyperthyroidism
- Diabetes
- Arthritis
- Pregnancy
- Obesity (BMI >30)
- Anatomical anomalies
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 60 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers
Clinical Trial Investigator Information
Lead Investigator: St. Antonius Hospital Other
Overall Clinical Trial Officials and Contacts
A.B. Mink van der Molen, dr. Principal Investigator St. Antonius Hospital
Overall Contact: Bo Verwer b.verwer@antoniusziekenhuis.nl
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT01081860
Study ID Number: STIF CTS
ClinicalTrials.gov Identifier: NCT01081860
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01081860
