Risk Factors of Recovery Room Delirium After Elective Non-cardiovascular Surgery

Official Title: “Risk Factors of Recovery Room Delirium After Elective Non-cardiovascular Surgery in Post-anaesthesia Care Unit”

Despite recent advances in postoperative delirium research, the proportion of patients with postoperative delirium is still high ranging between 20-80%. Although postoperative delirium is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for recovery room delirium (RRD) occurred in postanaesthesia care unit. The aim of the study was to determine pre- and intraoperative risk factors for the development of RRD among patients undergoing non cardiovascular surgery.

Recovery room delirium (RRD) defined as delirium occurred in PACU was diagnosed according to CAM-ICU criteria. Pre-, intra-, and postoperative data of patients undergoing elective non cardiovascular surgery were prospectively collected, univariate and multivariate logistic regression were performed to find the risk factors related to postoperative delirium.

Arms, Groups and Cohorts in this Clinical Trial

• : Delirium
  • Delirium was determined by CAM-ICU
• : no Delirium
  • no Delirium was determined by CAM-ICU

Primary Measures

• The presence of delirium in post anesthesia care unit (PACU) determined by confusion assessment method for the intensive care unit (CAM-ICU) criteria
  • Time Frame: within 1 hour after operation
    Safety Issue?: No

Secondary Measures

• heart rate in PACU
  • Time Frame: every 10 mins
    Safety Issue?: Yes
• Pulse Oximeter Oxygen Saturation (SpO2) in PACU
  • Time Frame: every 10 mins
    Safety Issue?: Yes
• Hospital-length of stay
  • Time Frame: up to 6 months
    Safety Issue?: Yes
• Total health care fees
  • Time Frame: up to 6 months
    Safety Issue?: Yes

Inclusion Criteria:

• elective non-cardiovascular surgery
• general anesthesia

Exclusion Criteria:

• under 18yr of age
• under regional anaesthesia
• refused to sign consent form
• history of substance dependence
• underwent neurosurgery
• history of primary neurologic diseases
• stayed less than 10min in PACU
• received general anaesthesia but recovered in locations outside the recovery room

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: N/A

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Lead Investigator: Huazhong University of Science and Technology Other

Overall Clinical Trial Officials and Contacts

Yuke Tian, MD. Study Chair Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology  

Information obtained from ClinicalTrials.gov on February 09, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00991913

Study ID Number: TJHMZK02001

ClinicalTrials.gov Identifier: NCT00991913

Health Authority: China: Health Department of Hubei Province