Deanxit and Rivotril in Tinnitus Patients

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The purpose of this study is to investigate whether increased tinnitus reduction can be obtained with Deanxit in patients already receiving Rivotril...

Brief Summary

Official Title: “Additional Value of Deanxit in Tinnitus Patients Treated With Rivotril”

The purpose of this study is to investigate whether increased tinnitus reduction can be obtained with Deanxit in patients already receiving Rivotril.

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
  • Study Primary Completion Date: July 2009

Intervention(s) in this Clinical Trial

  • Drug: Deanxit
    • Deanxit 1x/day
  • Drug: Lactose placebo
    • Lactose used as placebo

Arms, Groups and Cohorts in this Clinical Trial

  • Placebo Comparator: Lactose placebo
    • 1x/day
  • Experimental: Deanxit

Outcome Measures for this Clinical Trial

Primary Measures

  • Visual Analogue Scale
    • Time Frame: 3 weeks, 6 weeks
      Safety Issue?: No

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • pure tone, narrow band noise or polyphonic tinnitus
  • unilateral or bilateral tinnitus
  • VAS ≥ 4
  • cochleair origin tinnitus
  • tinnitus present 3 months or more
  • age 18y or more
  • intake Rivotril 1mg/d
  • patient 'able to cooperate'
  • patient able to fill in TQ en VAS
  • No pontine angle pathology on MRI

Exclusion Criteria:

  • pulsatile tinnitus
  • pregnancy or breast feeding
  • contra-indications Deanxit
  • recovery myocard infarct
  • conduction disorder His
  • untreated glaucoma
  • MAO inhibitors: 15d stop
  • otosclerosis
  • middle ear pathologies
  • Ménière
  • somatic tinnitus

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: N/A

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: University Hospital, Antwerp Other

Overall Clinical Trial Officials and Contacts

Olivier Meeus, MD Principal Investigator University Hospital, Antwerp  

Additional Information

Information obtained from ClinicalTrials.gov on February 02, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00841230

Study ID Number: 8/46/260

ClinicalTrials.gov Identifier: NCT00841230

Health Authority: Belgium: Federal Agency for Medicinal Products and Health Products

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00841230