Safety and IOP Lowering Efficacy of AL-6221
The purpose of this study is to compare the safety and IOP-lowering efficacy of various AL-6221 formulations in patients with open-angle glaucoma or ocular...
Brief Summary
The purpose of this study is to compare the safety and IOP-lowering efficacy of various AL-6221 formulations in patients with open-angle glaucoma or ocular hypertension
- Study Type: Interventional
- Study Design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
- Study Primary Completion Date: February 2008
Intervention(s) in this Clinical Trial
- Drug: AL-6221
- Comparison of safety and IOP lowering efficacy of different concentrations of AL-6221 with that of TRAVATAN
- Drug: TRAVATAN QD
- Comparison of safety and IOP lowering efficacy of different concentrations of TRAVATAN with that of AL-6221
- Drug: Placebo
- Vehicle
Arms, Groups and Cohorts in this Clinical Trial
- Experimental: 1
- AL-6221 0.0008% BID
- Experimental: 2
- AL-6221 0.001% BID
- Experimental: 3
- AL-6221 0.0012% BID
- Active Comparator: 4
- TRAVATAN QD
- Placebo Comparator: 5
- Vehicle
Outcome Measures for this Clinical Trial
Primary Measures
- Mean IOP
- Time Frame: From baseline
Safety Issue?: Yes
- Time Frame: From baseline
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Patients 18 years of age or older, either sex or race with open-angle glaucoma or confirmed ocular hypertension
Exclusion Criteria:
- Age related
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: N/A
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Investigator Information
Lead Investigator: Alcon Research Industry
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00637130
Study ID Number: C-06-11
ClinicalTrials.gov Identifier: NCT00637130
Health Authority: United States: Food and Drug Administration
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00637130
