Study of Intranasal Clonazepam in Adult Subjects With Epileptic Seizures

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Evaluate the safety and efficacy of intranasal Clonazepam in subjects with epilepsy...

Brief Summary

Official Title: “A Phase 2a, Open-label,Proof -Of-Concept Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Intranasal Clonazepam in Adult Subjects With Epileptic Seizures”

Evaluate the safety and efficacy of intranasal Clonazepam in subjects with epilepsy.

  • Study Type: Interventional
  • Study Design: Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
  • Study Primary Completion Date: December 2008

Intervention(s) in this Clinical Trial

  • Drug: Clonazepam
    • 1 Dose

Arms, Groups and Cohorts in this Clinical Trial

  • Experimental: 1

Outcome Measures for this Clinical Trial

Primary Measures

  • EEG
    • Time Frame: 1 Day
      Safety Issue?: No

Secondary Measures

  • Safety
    • Time Frame: 1 Day
      Safety Issue?: Yes

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • Diagnosis of refractory epilepsy
  • No Nasal conditions that would preclude the use of intranasal product

Exclusion Criteria:

  • Subject with a clinical significant unstable medical abnormality
  • Subject currently or regularly taking Clonazepam

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: 65 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: Jazz Pharmaceuticals Industry

Overall Clinical Trial Officials and Contacts

Beverly Benson, PhD Study Director Jazz Pharmaceuticals  

Additional Information

Information obtained from ClinicalTrials.gov on February 02, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00594945

Study ID Number: 07-001

ClinicalTrials.gov Identifier: NCT00594945

Health Authority: United States: Food and Drug Administration

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00594945