A Double Blind, Placebo Controlled Trial of Quetiapine in Anorexia Nervosa, a Dual Site Study
Research studies raise the possibility that medications such as quetiapine may improve mood or reduce obsessions in people with anorexia nervosa and may even help to normalize appetite. The medication quetiapine also known as seroquel works by activating certain systems in the brain, such as ones known as dopamine and serotonin chemical systems in the brain...
Brief Summary
Official Title: “A Double Blind, Placebo Controlled Trial of Quetiapine in Anorexia Nervosa, a Dual Site Study”
Research studies raise the possibility that medications such as quetiapine may improve mood or reduce obsessions in people with anorexia nervosa and may even help to normalize appetite. The medication quetiapine also known as seroquel works by activating certain systems in the brain, such as ones known as dopamine and serotonin chemical systems in the brain.
- Study Type: Interventional
- Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
- Study Primary Completion Date: December 2009
Intervention(s) in this Clinical Trial
- Drug: quetiapine
- quetiapine dosage will be titrated to subject tolerance beginning at 50 mg every 24 hours upwards to 400 mg every 24 hours.
Outcome Measures for this Clinical Trial
Primary Measures
- To determine efficacy of seroquel in anorexia nervosa
- Time Frame: 8 weeks
Safety Issue?: No
- Time Frame: 8 weeks
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Must be aged 18-65
- Must be at least 15% below ideal body weight
Exclusion Criteria:
- Allergy to quetiapine
- Diagnosis of schizophrenia
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 65 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Investigator Information
Lead Investigator: University of South Florida Other
Overall Clinical Trial Officials and Contacts
Overall Contact: Patti Lowery 813.974.2415 plowery@health.usf.edu
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00584688
Study ID Number: 0825
ClinicalTrials.gov Identifier: NCT00584688
Health Authority: United States: Institutional Review Board
USF Health Clinical Studies/Principal Investigator: Pauline Powers,MD
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00584688
