Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

Official Title: “Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)”

The primary aims of this study are to assess:

1. The inter-rater and test-retest reliability of the MINI-KID

2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and th longer clinician rated "Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) and "expert opinion" (when available).

Secondary aims will include evaluating the concordance between: The Children's Global Assessment Scale (a required part of the K-SADS) with the clinician-rated Sheehan Disability Scale (to be administered with the MINI-KID) as a measure of illness severity.

The MINI-KID is a short, structured diagnostic interview used to assess the presence of 24 DSM-IV child and adolescent psychiatric disorders as well as the risk of suicide.

To achieve adequate representation of the major psychiatric disorders and sufficient normal controls, we propose recruiting 230 children and adolescents (ages 6 to 17 years 11 months), comprised of 200 subjects identified as having one or more psychiatric disorders and 30 normal controls in the community. These subjects will be from diverse socioeconomic, racial and ethnic backgrounds. We will assess the inter-rater and test-retest reliability of the MINI-KID and examine its validity with the "gold-standard" diagnostic interview for children and adolescents as well as expert opinion.

Intervention(s) in this Clinical Trial

• Other: MINI-KID
  • Structured Diagnostic Interview for children and adolescent psychiatric disorders.

Primary Measures

• Kappa scores between MINI Kid and K-SADS
  • Time Frame: 4 years
    Safety Issue?: No

Inclusion Criteria:

• Subjects will be between the ages of 6 years and 17 years, 11 months
• All subjects must meet MINI-KID DSM-IV criteria for a least one of the Axis I child psychiatry disorders covered by the MINI-KID.
• Both sexes are included.

Exclusion Criteria:

• Subjects who suffer from mental retardation, significant developmental disorders, congenital abnormalities, delirium, dementia, a language problem, or brain damage will be excluded.
• Subjects with neurological disorders, chronic or life threatening diseases will be excluded.

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 6 Years

Maximum Age for this Clinical Trial: 17 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers

Lead Investigator: University of South Florida Other

Overall Clinical Trial Officials and Contacts

David V. Sheehan, MD, MBA Principal Investigator University of South Florida College of Medicine  

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00579267

Study ID Number: MINI-KID Validation Study

ClinicalTrials.gov Identifier: NCT00579267

Health Authority: United States: Institutional Review Board