Melatonin and Adiponectin in Hypertensive Kidney Transplant
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients. The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus "normal" hypertensive patients. Secondly, to ask...
Brief Summary
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome.
We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.
The aim of this study is to find whether there is a difference between melatonin secretion in hypertensive kidney recipients versus "normal" hypertensive patients. Secondly, to ask if there is any correlation between melatonin secretion and adiponectin levels.
- Study Type: Observational
- Study Design: Observational Model: Case Control, Time Perspective: Prospective
Arms, Groups and Cohorts in this Clinical Trial
- : 1
- kidney transplant with hypertension
- : 2
- hypertensive patients with native kidneys
- : 3
- healthy controls
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- hypertension
- kidney transplantation ( group 1)
- good renal function
Exclusion Criteria:
- diabetes mellitus
- cancer
- renal failure
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 70 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers
Clinical Trial Investigator Information
Lead Investigator: Sheba Medical Center Other
Overall Clinical Trial Officials and Contacts
Avshalom Leibowitz, MD Principal Investigator
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00498576
Study ID Number: SHEBA-07-4730-AL-CTIL
ClinicalTrials.gov Identifier: NCT00498576
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00498576
