Is There is a Role of Prophylactic Therapy With Tamsulosin Before Extracorporeal Shock Wave Lithotripsy to Avoid Development of Steinstrasse ?

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The purpose of this study is to determine if there is a role of prophylactic therapy with tamsulosin prior extracorporeal shock wave lithotripsy to avoid development of steinstrasse. 150 persons that will go to Extracorporeal shock wave lithotripsy will randomize to 2 groups. Group 1 -of 75 persons will recieve tamsulosin 0.4 mg x 1/d 2 days before the lithotripsy . Group 2 - of 75 persons will...

Brief Summary

The purpose of this study is to determine if there is a role of prophylactic therapy with tamsulosin prior extracorporeal shock wave lithotripsy to avoid development of steinstrasse.

150 persons that will go to Extracorporeal shock wave lithotripsy will randomize to 2 groups.

Group 1 -of 75 persons will recieve tamsulosin 0.4 mg x 1/d 2 days before the lithotripsy .

Group 2 - of 75 persons will not recieve tamsulosin. 48 hour after the ESWL all 2 group will take abdominal radiograph to evaluate the presence of steinstrasse.

  • Study Type: Observational
  • Study Design: Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal, Time Perspective: Prospective

Intervention(s) in this Clinical Trial

  • Drug: tamsulosin 0.4mg

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • size of stone 1-2 cm

Exclusion Criteria:

  • ureteral stricture Presence of internal stent prior use of alfa bloker prior ESWL

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 15 Years

Maximum Age for this Clinical Trial: 85 Years

Clinical Trial Investigator Information

Lead Investigator: HaEmek Medical Center, Israel Other

Overall Clinical Trial Officials and Contacts

doron perez Principal Investigator Urology department: Haemek Medical Center  

Overall Contact: DORON PEREZ, M.D. +972-4-6495115 perez_do@clalit.org.il

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00489723

Study ID Number: 0056-07-EMC

ClinicalTrials.gov Identifier: NCT00489723

Health Authority: Israel: Ethics Commission

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http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00489723