Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers

Official Title: “Preventing Postpartum Depression in Adolescent Mothers”

This study will aim to prevent postpartum depression in pregnant teenagers through an interpersonal therapy-based program.

Postpartum depression is believed to be one of the most common complications after pregnancy. This type of depression often occurs within the first year after the baby is born and is most likely caused by dramatic changes in hormone levels after pregnancy. Pregnant teenagers are even more at risk for experiencing complications throughout pregnancy and parenting difficulties after delivery. Minimal research has been done on preventive ways to reduce postpartum depression in teenagers. Therefore, this study will evaluate the effectiveness of an interpersonal therapy-based program at preventing postpartum depression in financially disadvantaged pregnant teenagers.

Participants will first undergo a 15-minute interview about their background and emotions.

Participants will undergo a second interview and then be randomly assigned to receive either interpersonal therapy-based treatment or standard care. Participants assigned to receive interpersonal therapy-based treatment will focus on the psychological aspects of pregnancy and factors that may play a role in the development of postpartum depression in teenage mothers, such as poor social support, role transitions, and life stressors. Participants assigned to receive standard care will focus more on the health issues associated with pregnancy and postpartum. Both groups will attend weekly 1-hour sessions for 5 weeks.

Homework may be assigned to review topics discussed, and all participants will receive the book Baby Basics. Following treatment, participants will meet with researchers again when they are 34 to 36 weeks pregnant; in the hospital after the baby is born; and 6, 12, and 24 weeks after the baby is born.

Intervention(s) in this Clinical Trial

• Behavioral: Interpersonal therapy-based treatment
  • Participants assigned to receive interpersonal therapy-based treatment will focus on the psychological aspects of pregnancy and factors that may play a role in the development of postpartum depression in teenage mothers, such as poor social support, role transitions, and life stressors. Both groups will attend weekly 1-hour sessions for 5 weeks.
• Behavioral: Standard care
  • Participants assigned to receive standard care will focus more on the health issues associated with pregnancy and postpartum. Both groups will attend weekly 1-hour sessions for 5 weeks.

Arms, Groups and Cohorts in this Clinical Trial

• Experimental: A
  • Participants will receive interpersonal therapy-based treatment
• Active Comparator: B
  • Participants will receive standard care

Primary Measures

• Postpartum depression diagnosis
  • Time Frame: Measured at pretreatment; Weeks 34 to 36 during pregnancy; hospital stay after delivery; and Weeks 6, 12, and 24 postpartum
    Safety Issue?: No

Secondary Measures

• Degree of depressive symptoms
  • Time Frame: Measured at pretreatment; Weeks 34 to 36 during pregnancy; hospital stay after delivery; and Weeks 6, 12, and 24 postpartum
    Safety Issue?: No
• Prenatal distress
  • Time Frame: Measured at pretreatment; Weeks 34 to 36 during pregnancy; hospital stay after delivery; and Weeks 6, 12, and 24 postpartum
    Safety Issue?: No
• Social support
  • Time Frame: Measured at pretreatment; Weeks 34 to 36 during pregnancy; hospital stay after delivery; and Weeks 6, 12, and 24 postpartum
    Safety Issue?: No

Inclusion Criteria:

• Less than 24 weeks pregnant
• Not currently being treated for depression
• Speaks and reads English fluently

Exclusion Criteria:

• Currently receiving mental health services from a health care provider
• Meets DSM-IV criteria for an affective disorder, substance use disorder, or psychosis

Gender Eligibility for this Clinical Trial: Female

Minimum Age for this Clinical Trial: 12 Years

Maximum Age for this Clinical Trial: 18 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers

Lead Investigator: National Institute of Mental Health (NIMH) NIH

Overall Clinical Trial Officials and Contacts

Maureen Phipps, MD Principal Investigator Women and Infants Hospital of Rhode Island  

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00436150

Study ID Number: R34 MH077588

ClinicalTrials.gov Identifier: NCT00436150

Health Authority: United States: Federal Government