Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes
To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes...
Brief Summary
To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.
- Study Type: Interventional
- Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Intervention(s) in this Clinical Trial
- Drug: Acarbose
Outcome Measures for this Clinical Trial
Primary Measures
- Postprandial hyperglycemia
Secondary Measures
- Postprandial inflammatory responses
- Postprandial oxidative stress
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- Subjects with mild diabetes without prior medications or impaired glucose tolerance
Exclusion Criteria:
- Pregnancy
- Recent major cardiac, renal and hepatic disease
- Intolerance to alcohol
- Allergy to acarbose treatment
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 25 Years
Maximum Age for this Clinical Trial: 75 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Investigator Information
Lead Investigator: Taichung Veterans General Hospital Other
Overall Clinical Trial Officials and Contacts
Wayne H Sheu, MD, PhD Principal Investigator Taichung Veterans General Hospital
Overall Contact: I Te Lee, MD, MS 886-4-23592525 itlee@vghtc.gov.tw
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00417950
Study ID Number: 950801/C06138
ClinicalTrials.gov Identifier: NCT00417950
Health Authority: Taiwan: Department of Health
Clinical Trials content is provided directly by the U.S. National Institutes of Health via ClinicalTrials.gov and is not reviewed separately by ClinicalTrialsFeeds.org. Every page of specific clinical trials information contains a unique identifier which can be used to find further details directly from the National Institutes of Health.
The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00417950
