24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients

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The purpose of this study is to compare the short-term mean 24-hour intraocular pressure control, 24-hour blood pressure effect and safety of Latanoprost/Timolol fixed combination given once in the evening with placebo once in the morning versus timolol maleate 0.5% given twice daily in patients with ocular hypertension and primary open-angle glaucoma...

Brief Summary

Official Title: “24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients”

The purpose of this study is to compare the short-term mean 24-hour intraocular pressure control, 24-hour blood pressure effect and safety of Latanoprost/Timolol fixed combination given once in the evening with placebo once in the morning versus timolol maleate 0.5% given twice daily in patients with ocular hypertension and primary open-angle glaucoma.

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment
  • Study Primary Completion Date: April 2007

Intervention(s) in this Clinical Trial

  • Drug: timolol maleate 0.5%
  • Drug: latanoprost/timolol fixed combination
  • Drug: placebo (artificial tears)

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • POAG
  • OHT

Exclusion Criteria:

  • Advanced glaucoma
  • Arterial Hypertension

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 29 Years

Maximum Age for this Clinical Trial: 80 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: Aristotle University Of Thessaloniki Other

Overall Clinical Trial Officials and Contacts

AGP Konstas, MD, PhD Principal Investigator Glaucoma Unit, A University Dept of Ophthalmology, AHEPA Hospital  

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00330577

Study ID Number: A594

ClinicalTrials.gov Identifier: NCT00330577

Health Authority: Greece: National Organization of Medicines

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00330577