Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole
The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation...
Brief Summary
Official Title: “Enhancement of Postocclusive Reactive Hyperaemia”
The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.
- Study Type: Interventional
- Study Design: Allocation: Non-Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science
Intervention(s) in this Clinical Trial
- Drug: dipyridamole
- Drug: caffeine
Outcome Measures for this Clinical Trial
Primary Measures
- forearm blood flow
Criteria for Participation in this Clinical Trial
Inclusion Criteria:
- healthy volunteers between 18 and 50 years
Exclusion Criteria:
- none specified
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 50 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers
Clinical Trial Investigator Information
Lead Investigator: Radboud University Other
Overall Clinical Trial Officials and Contacts
Gerard Rongen, MD,PhD Principal Investigator Radboud University
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00268554
Study ID Number: PORH-dipy
ClinicalTrials.gov Identifier: NCT00268554
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00268554
