Fexofenadine in Pruritic Skin Disease

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Primary objective: - To compare the efficacy and safety profile of Fexofenadine 180mg tablets plus prednicarbate(2.5mg/g) vs prednicarbate(2.5mg/g) alone in the treatment of pruritic skin disease Secondary objective: - To evaluate patient's satisfaction of Allegra...

Brief Summary

Official Title: “The Evaluation of Efficacy and Safety of Fexofenadine 180mg Tablets for 7 Days in the Treatment of Pruritic Skin Disease”

Primary objective: - To compare the efficacy and safety profile of Fexofenadine 180mg tablets plus prednicarbate(2.5mg/g) vs prednicarbate(2.5mg/g) alone in the treatment of pruritic skin disease

Secondary objective: - To evaluate patient's satisfaction of Allegra treatment

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Intervention(s) in this Clinical Trial

  • Drug: Fexofenadine

Outcome Measures for this Clinical Trial

Primary Measures

  • The change of physician's assessment on pruritic score before and after 7-day treatment.

Secondary Measures

  • Patient visual analogue scale change and Overall satisfaction.

Criteria for Participation in this Clinical Trial

  • The following information on clinical trials is provided for information purposes only to allow patients and physicians to have an initial discussion about the trial. This information is not intended to be complete information about the trial, to contain all considerations that may be relevant to potential participation in the trial, or to replace the advice of a personal physician or health professional.
  • Main criteria are listed hereafter:

    Inclusion Criteria:

    • All patients diagnosed with atopic dermatitis, contact dermatitis

    Exclusion Criteria:

    • Other skin disease except atopic dermatitis, contact dermatitis.
    • Subjects taken steroid within 4 weeks and antihistamine within 1 week before screening day.
    • Pruritus localized only head and face
    • Subjects with severe hepatic, renal, heart dysfunction.
    • Subjects with history of alcohol and drug abuse.
    • Pregnant and lactating women.

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 12 Years

Maximum Age for this Clinical Trial: 70 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: Handok Pharmaceuticals Co., Ltd. Industry

Overall Clinical Trial Officials and Contacts

Hyou-Young Rhim, MD Study Director Handok Pharmaceuticals Co., Ltd.  

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00261079

Study ID Number: M016455_4125

ClinicalTrials.gov Identifier: NCT00261079

Health Authority: South Korea: Korea Food and Drug Administration (KFDA)

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00261079