The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Bipolar Disorder I or II This Study is Not Being Conducted in the United States.

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Bipolar disorder is a psychiatric illness with clinical characteristics of mixed mania, grandiose delusions, and suicidality. This study will investigate the efficacy a safety of oxcarbazepine in the treatment of patients with bipolar disorder type I or II...

Brief Summary

Official Title: “A Multi-center, Randomized, Double-blind, Parallel Group, Placebo-controlled 52 Weeks Clinical Trial to Evaluate Efficacy and Safety of Oxcarbazepine p.o.(300-1200 mg/Day) as Adjuvant Therapy in the Bipolar Disorder I or II Treatment”

Bipolar disorder is a psychiatric illness with clinical characteristics of mixed mania, grandiose delusions, and suicidality. This study will investigate the efficacy a safety of oxcarbazepine in the treatment of patients with bipolar disorder type I or II.

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
  • Study Primary Completion Date: January 2006

Intervention(s) in this Clinical Trial

  • Drug: Oxcarbazepine

Outcome Measures for this Clinical Trial

Primary Measures

  • Duration of remission

Secondary Measures

  • Daily mood fluctuation
  • Time to new maniac/hypomanic episode
  • Time to new depressive episode
  • Number of relapsed patients at study completion and type/severity of episode
  • Change from baseline in functional activity

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • History of bipolar disorder type I or II

Exclusion Criteria:

  • Other serious medical conditions
  • Treatment with antiepileptic medications
  • Other protocol-defined inclusion/exclusion criteria may apply.

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: N/A

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: Novartis Industry

Overall Clinical Trial Officials and Contacts

Eduard Vieta, MD Principal Investigator Hospital Clinic, Universitary of Barcelona  

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00154323

Study ID Number: CTRI476BES03

ClinicalTrials.gov Identifier: NCT00154323

Health Authority: Spain: Ministry of Health

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00154323