A Study to Investigate a Research Drug as an Aid for Smoking Cessation in Chronic Cigarette Smokers

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The purpose of this study is to evaluate the safety and tolerability of an investigational drug that may help individuals to stop smoking...

Brief Summary

Official Title: “A Double-Blind, Multicenter, Randomized, Titrated-Dose, Placebo-Controlled, Study of MK0364 (4 mg to 8 mg) in Chronic Cigarette Smokers as an Aid for Smoking Cessation”

The purpose of this study is to evaluate the safety and tolerability of an investigational drug that may help individuals to stop smoking.

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
  • Study Primary Completion Date: June 2005

Intervention(s) in this Clinical Trial

  • Drug: taranabant

Outcome Measures for this Clinical Trial

Primary Measures

  • Quitting smoking after 8 weeks of treatment by measuring lab values and expired breath CO levels
    • Time Frame: after 8 weeks of treatment
      Safety Issue?: No

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • Smoking greater than/equal to 10 cigarettes/day for at least 1 year
  • Laboratory tests that meet the criteria of the study
  • In overall good health as determined by the investigator

Exclusion Criteria:

  • Psychiatric diagnoses
  • Certain cancers
  • Patients who use nicotine replacement therapy
  • Patients on a diet regimen

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 18 Years

Maximum Age for this Clinical Trial: 65 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: Accepts Healthy Volunteers

Clinical Trial Investigator Information

Lead Investigator: Merck Industry

Overall Clinical Trial Officials and Contacts

Medical Monitor Study Director   

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00109135

Study ID Number: 2005_012

ClinicalTrials.gov Identifier: NCT00109135

Health Authority: United States: Food and Drug Administration

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00109135