Combined Behavioral/Pharmacological Therapy for Insomnia

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This study will determine how sleeping pills can be combined with nondrug treatments to maximize the benefits of therapy for insomnia...

Brief Summary

Official Title: “Combined Behavioral/Pharmacological Therapy for Insomnia”

This study will determine how sleeping pills can be combined with nondrug treatments to maximize the benefits of therapy for insomnia.

  • Study Type: Interventional
  • Study Design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Detailed Clinical Trial Description

Long-term insomnia is a common and significant health problem. Two main treatments, pharmacotherapy and behavioral therapy, have been used to help people with insomnia. Because both treatments have advantages and disadvantages, a combination of these treatments may be a good way to treat insomnia.

During the first 2 weeks of the study, participants keep a sleep log, wear an actigraph (a device that resembles a wristwatch and records activity to help determine when participants are asleep or awake), and complete questionnaires.

Participants are then randomly assigned to receive 6 weeks of behavioral therapy plus zolpidem tartrate (Ambien), behavioral therapy plus placebo, or behavioral therapy alone.

During treatment, participants return to the clinic once a week to turn in their sleep logs, download their actigraph, and complete questionnaires.

After 6 weeks, participants enter the post-treatment phase of the study, which lasts 2 weeks and is identical to the 2-week assessment at the beginning of the study.

After the post-treatment phase, participants enter the follow-up period and are contacted at 3 months, 6 months, and 1 year to complete another 2-week assessment with sleep logs, actigraphy, and questionnaires.

Intervention(s) in this Clinical Trial

  • Behavioral: Cognitive-Behavioral Therapy for Insomnia
  • Drug: zolpidem tartrate (Ambien)

Criteria for Participation in this Clinical Trial

Inclusion Criteria:

  • Chronic primary insomnia which includes at least 6 months of trouble falling asleep or staying asleep

Gender Eligibility for this Clinical Trial: Both

Minimum Age for this Clinical Trial: 21 Years

Maximum Age for this Clinical Trial: 75 Years

Are Healthy Volunteers Accepted for this Clinical Trial?: No

Clinical Trial Investigator Information

Lead Investigator: National Institute of Mental Health (NIMH) NIH

Additional Information

Information obtained from ClinicalTrials.gov on February 12, 2012

Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00044629

Study ID Number: R01 MH62119

ClinicalTrials.gov Identifier: NCT00044629

Health Authority: United States: Federal Government

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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00044629