Cocaine Effects in Humans: Physiology and Behavior - 1
The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users...
Brief Summary
Official Title: “Cocaine Effects in Humans: Physiology and Behavior”
The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.
- Study Type: Interventional
- Study Design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment
- Study Primary Completion Date: January 1998
Intervention(s) in this Clinical Trial
- Drug: Methadone
- normal maintenance dose
Outcome Measures for this Clinical Trial
Primary Measures
- Interaction of cocaine and meds on cardio
- Time Frame: 3 hr
Safety Issue?: Yes
- Time Frame: 3 hr
- Interaction of cocaine & meds on coc's subjective
- Time Frame: 3 hr
Safety Issue?: Yes
- Time Frame: 3 hr
- Effects of medication on cocaine craving
- Time Frame: 3 hr
Safety Issue?: No
- Time Frame: 3 hr
Criteria for Participation in this Clinical Trial
- Please contact site for information.
Gender Eligibility for this Clinical Trial: Both
Minimum Age for this Clinical Trial: 18 Years
Maximum Age for this Clinical Trial: 45 Years
Are Healthy Volunteers Accepted for this Clinical Trial?: No
Clinical Trial Investigator Information
Lead Investigator: National Institute on Drug Abuse (NIDA) NIH
Overall Clinical Trial Officials and Contacts
Marian Fischman, Ph.D. Principal Investigator Columbia University
Related Publications
Citations Reporting Results
Foltin RW, Fischman MW. Effects of methadone or buprenorphine maintenance on the subjective and reinforcing effects of intravenous cocaine in humans. J Pharmacol Exp Ther. 1996 Sep;278(3):1153-64.
Additional Information
Information obtained from ClinicalTrials.gov on February 12, 2012
Link to the current ClinicalTrials.gov record. http://clinicaltrials.gov/show/NCT00000200
Study ID Number: NIDA-03818-1
ClinicalTrials.gov Identifier: NCT00000200
Health Authority: United States: Federal Government
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The URL of this page is:
http://clinicaltrialsfeeds.org/clinical-trials/show/NCT00000200
