Clinical Trials News Feeds and Updates: Welcome
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Clinical Trials Updates via RSS Feed
You can receive a summary of all the most recently updated trials via RSS. Note that the 7-day, 14-day and 21-day feeds can often be very large. (We’ve capped the total feed size at 50 entries, but that’s still quite a few.)
- Clinical Trials RSS Feed: Last 3 Days of Updates
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Summary of Clinical Trials Updates During the Last 5 Days
The following includes a selection of the clinical trials available which have been updated during the last 5 days. We’ve capped the total number displayed here at 50, but for some 5 day periods, the actual total may be significantly higher.
- Gene Expression in Predicting Outcome in Samples From Patients With High-Risk NeuroblastomaThu, 26 Jan 2012Condition: Neuroblastoma
Interventions: Genetic: RNA analysis; Genetic: gene expression analysis; Other: laboratory biomarker analysis
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified January 2012 - Gene Expression in Samples From Patients With T-Cell Acute Lymphoblastic LeukemiaThu, 26 Jan 2012Conditions: Leukemia; Lymphoma
Interventions: Genetic: gene expression analysis; Other: laboratory biomarker analysis
Sponsors: Children's Oncology Group; National Cancer Institute (NCI)
Active, not recruiting - verified January 2012 - Tivantinib in Treating Patients With Metastatic Prostate CancerWed, 25 Jan 2012Condition: Prostate Cancer
Interventions: Drug: tivantinib; Other: placebo
Sponsors: Arthur G. James Cancer Hospital & Richard J. Solove Research Institute; National Cancer Institute (NCI)
Recruiting - verified January 2012 - Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular HypertensionWed, 25 Jan 2012Condition: Primary Open Angle Glaucoma and Ocular Hypertension
Interventions: Drug: Stage 1 - ATS907 - Formulation 1; Drug: Stage 1 - ATS907 - Formulation 2; Drug: Stage 1 - ATS907 - Formulation 3; Drug: Stage 1 - ATS907 - Formulation 4; Drug: Stage 1 - Vehicle; Drug: Stage 2 - ATS907 - Formulation 1 - to be selected from Stage 1; Drug: Stage 2 - ATS907 - Formulation 2 - to be selected from Stage 1; Drug: Latanoprost 0.005%
Sponsor: Altheos, Inc.
Recruiting - verified January 2012 - Polyp Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Subjects Undergoing Outpatients ColonoscopyWed, 25 Jan 2012Condition: Polyp and Adenoma Detection During Colonoscopy
Intervention: Device: oral tablet dye for detection of polyps during colonoscopy
Sponsor: Cosmo Technologies Ltd
Active, not recruiting - verified January 2012 - Selumetinib With or Without Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or DabrafenibWed, 25 Jan 2012Condition: Melanoma (Skin)
Interventions: Drug: Akt inhibitor MK2206; Drug: selumetinib
Sponsors: H. Lee Moffitt Cancer Center and Research Institute; National Cancer Institute (NCI)
Recruiting - verified January 2012 - Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic HypotensionWed, 25 Jan 2012Condition: Intra-dialytic Hypotension
Interventions: Drug: Mannitol (20%); Drug: 0.9% saline
Sponsor: Brigham and Women's Hospital
Not yet recruiting - verified January 2012 - Mepolizumab Treatment for Rhinovirus-induced Asthma ExacerbationsWed, 25 Jan 2012Conditions: Asthma; Viral Infection
Intervention: Drug: Mepolizumab
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); The Netherlands Asthma Foundation; GlaxoSmithKline
Recruiting - verified January 2012 - Adjuvant Proton Therapy or IMRT for the Treatment of Bladder CancerWed, 25 Jan 2012Condition: Urothelial Carcinoma of the Bladder
Interventions: Radiation: Proton therapy; Radiation: IMRT
Sponsor: Abramson Cancer Center of the University of Pennsylvania
Recruiting - verified January 2012 - Low-Dose Adjunctive Aripiprazole in the Treatment of Bipolar Depression: Double-Blind Placebo-Controlled Pilot StudyWed, 25 Jan 2012Conditions: Bipolar Disorder; Depressive Episode
Intervention: Drug: Low dose Adjunctive Aripiprazole
Sponsors: Serge Beaulieu; Bristol-Myers Squibb
Not yet recruiting - verified January 2012 - Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs. Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast CancerWed, 25 Jan 2012Conditions: Her2-negative Metastatic Breast Cancer; Her2-negative Locally Advanced Breast Cancer
Interventions: Drug: Vinorebine, Everolimus; Drug: Vinorelbine
Sponsor: AIO-Studien-gGmbH
Not yet recruiting - verified January 2012 - Intraepithelial Neoplasia Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Patients With Long Standing Ulcerative Colitis Undergoing ColonoscopyWed, 25 Jan 2012Condition: Long Standing Ulcerative Colitis
Intervention: Device: oral delivery mucosal stain
Sponsor: Cosmo Technologies Ltd
Recruiting - verified January 2012 - A Study of Drug-Drug Interaction Between Darunavir and Danoprevir Administered Together With Low-Dose Ritonavir in Healthy VolunteersTue, 24 Jan 2012Condition: Healthy Volunteer
Interventions: Drug: danoprevir; Drug: darunavir; Drug: ritonavir
Sponsor: Hoffmann-La Roche
Not yet recruiting - verified January 2012 - Age-Associated Changes in Regional Adiposity and Novel Cardiovascular Risk FactorsTue, 24 Jan 2012Conditions: Hypertension; Atherosclerosis
Intervention:
Sponsor: National Institute on Aging (NIA)
Recruiting - verified September 2011 - The Roles of Endocannabinoids in Insulin Secretion and ActionTue, 24 Jan 2012Conditions: Glucose Metabolism; Insulin Resistance
Interventions: Drug: CP-945,598; Procedure: Hypoglycemic Clamp; Procedure: Euglycemic-Hyperinsulinemic Clamp
Sponsor: National Institute on Aging (NIA)
Recruiting - verified October 2011 - Pilot Study of Interpersonal and Social Rhythm Therapy for Subthreshold BipolarTue, 24 Jan 2012Condition: Bipolar Disorder NOS
Intervention: Other: Interpersonal and social rhythm therapy
Sponsors: University of Pittsburgh; The Depressive and Bipolar Disorder Alternative Treatment Foundation
Not yet recruiting - verified January 2012 - Impact of Disease on the Concept of End-of-life Decisions of the Elderly in the CommunityTue, 24 Jan 2012Condition: Sick Elderly
Intervention: Other: Questionnaire
Sponsor: Meir Medical Center
Not yet recruiting - verified January 2012 - Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral AzacitidineTue, 24 Jan 2012Conditions: Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Leukemia, Myeloid, Acute
Interventions: Drug: oral azacitidine; Drug: oral azacitidine
Sponsor: Celgene Corporation
Recruiting - verified January 2012 - How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary InterventionTue, 24 Jan 2012Condition: Acute ST Elevation Myocardial Infarction
Interventions: Drug: unfractionated heparin; Drug: Bivalirudin
Sponsor: Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting - verified January 2012 - Improving Blood Stem Cell Collection and Transplant ProceduresTue, 24 Jan 2012Conditions: Myelodysplastic Syndrome (MDS); Chronic Myelogenous Leukemia; Acute Lymphoblastic Leukemia; CML (Chronic Myelogenous Leukemia; CLL (Chronic Lymphocytic Leukemia); Acute Myeloid Leukemia (AML)
Intervention: Procedure: Stem Cell Transplantation
Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified August 2011 - Role of Serum Total Antioxidant Level in Preterm LaborTue, 24 Jan 2012Condition: Preterm Labor
Intervention:
Sponsor: Ain Shams Maternity Hospital
Recruiting - verified January 2012 - Diabetes in Europe - Prevention Using Lifestyle, Physical Activity and Nutritional Intervention in CataloniaTue, 24 Jan 2012Condition: Type 2 Diabetes Mellitus
Intervention: Behavioral: Lifestyle intervention
Sponsors: Jordi Gol i Gurina Foundation; Instituto de Salud Carlos III; Departament de Salut de la Generalitat de Catalunya
Active, not recruiting - verified January 2012 - Comparison of Temazepam and Acetazolamide to Treat Difficulty Sleeping at High AltitudeTue, 24 Jan 2012Condition: High-altitude Sleep Disturbance
Interventions: Drug: Temazepam; Drug: Acetazolamide
Sponsor: Massachusetts General Hospital
Not yet recruiting - verified January 2012 - Ascending Multiple-Dose Study to Evaluate VIA-3196 in Healthy SubjectsTue, 24 Jan 2012Condition: Drug Safety
Interventions: Drug: Placebo; Drug: VIA-3196
Sponsor: Madrigal Pharmaceuticals, Inc.
Not yet recruiting - verified January 2012 - Testing a Spanish Version of a Patient Toxicity QuestionnaireTue, 24 Jan 2012Condition: Cancer
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified November 2011 - ROLE OF PROCALCITONIN IN DIFFERANTIATION BETWEEN BACTERIAL Infection AND NON-INFECTIOUS INFLAMATION IN FEBRILE Hepatocellular Carcinoma PATIENTS After Locoregional TreatmentTue, 24 Jan 2012Condition: Hepatocellular Carcinoma
Intervention:
Sponsor: Ain Shams University
Not yet recruiting - verified January 2012 - Randomized Comparison of Sharp Versus Blunt Techniques at CesareanTue, 24 Jan 2012Condition: Disruption of Uterine Incision After Cesarean Section
Intervention:
Sponsor: Istanbul Bakirkoy Maternity and Children Diseases Hospital
Active, not recruiting - verified January 2012 - Assessing Suicide Risk in Adolescents With Developmental DelaysTue, 24 Jan 2012Condition: Child Development Disorders, Pervasive
Intervention:
Sponsor: National Institute of Mental Health (NIMH)
Recruiting - verified November 2011 - Diet and Nutrition Pilot Study for Chinese Adolescents and Their MothersTue, 24 Jan 2012Condition: In Utero Exposure
Intervention:
Sponsor: National Cancer Institute (NCI)
Recruiting - verified November 2011 - Comparison of Closed-loop Operation After Morning Meal With and Without Carbohydrate CountingTue, 24 Jan 2012Condition: Type-1 Diabetes
Intervention: Device: Dual Hormone closed-loop system
Sponsors: Institut de Recherches Cliniques de Montreal; McGill University Center for Intelligent Machines; Montreal Children's Hospital
Recruiting - verified January 2012 - Brain-Derived Neurotrophic Factor in Obesity and Brain FunctionTue, 24 Jan 2012Conditions: Obesity; Genetic Disorder; Mental Retardation; Developmental Delay
Intervention:
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting - verified November 2011 - Markers and Response to Cardiac Resynchronization TherapyTue, 24 Jan 2012Condition: Heart Failure
Intervention: Device: CRT-D (Medtronic)
Sponsors: University Medical Centre Groningen; Center for Translational Molecular Medicine; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); UMC Utrecht; Maastricht University Medical Center; Free University Medical Center
Not yet recruiting - verified January 2012 - Interaction Between a Calcimimetic Agent and the RAASTue, 24 Jan 2012Condition: Relationship Between Calcimimetic and the RAAS
Interventions: Drug: calcimimetic agent (cinacalcet); Drug: placebo
Sponsors: Centre Hospitalier Universitaire Vaudois; Swiss National Science Foundation
Recruiting - verified January 2012 - THE SAFETY, EFFECTIVENESS, AND PHARMACOKINETICS OF AA4500 FOR THE TREATMENT OF EDEMATOUS FIBROSCLEROTIC PANNICULOPATHY (COMMONLY KNOWN AS CELLULITE)Tue, 24 Jan 2012Conditions: Edematous Fibrosclerotic Panniculopathy; Cellulite
Intervention: Biological: COLLAGENASE CLOSTRIDIUM HISTOLYTICUM
Sponsor: Auxilium Pharmaceuticals
Recruiting - verified January 2012 - Reducing Asthma Morbidity In High Risk Minority Preschool ChildrenTue, 24 Jan 2012Condition: Asthma
Intervention: Behavioral: Home Based Asthma Education
Sponsor: Johns Hopkins University
Recruiting - verified January 2012 - Follistatin Gene Transfer to Patients With Becker Muscular Dystrophy and Sporadic Inclusion Body MyositisMon, 23 Jan 2012Conditions: Becker Muscular Dystrophy; Sporadic Inclusion Body Myositis
Intervention: Genetic: rAAV1.CMV.huFollistatin344
Sponsor: Nationwide Children's Hospital
Enrolling by invitation - verified January 2012 - Study of a Diagnostic Device for Identifying Between Amniotic Fluid to UrineMon, 23 Jan 2012Condition: Amniotic Fluid Leakage
Intervention: Device: BirthSign
Sponsor: Hadassah Medical Organization
Active, not recruiting - verified January 2012 - General Anesthesia vs. Local Anesthesia in StereotaxyMon, 23 Jan 2012Condition: Brain Lesion, Stereotactic Biopsy
Interventions: Procedure: general anesthesia in stereotactic biopsy; Procedure: local anesthesia in stereotactic biopsy
Sponsor: Johann Wolfgang Goethe University Hospitals
Not yet recruiting - verified January 2012 - BiPAP-Vapotherm RCTMon, 23 Jan 2012Condition: Advanced Cancers
Interventions: Device: Oxygen Delivery Devices; Behavioral: Questionnaires
Sponsor: M.D. Anderson Cancer Center
Not yet recruiting - verified January 2012 - Gut Flora Dependent Metabolism of Dietary Phosphatidylcholine and Cardiovascular DiseaseMon, 23 Jan 2012Condition: Nutrition
Intervention: Other: Antibiotic (metronidazole and ciprofloxacin)/probiotic
Sponsor: The Cleveland Clinic
Enrolling by invitation - verified January 2012 - Postural Control in Breast HypertrophyMon, 23 Jan 2012Conditions: Hypertrophy; Sensation Disorders
Intervention:
Sponsor: University of Sao Paulo General Hospital
Completed - verified January 2012 - A Study That Provides Long-term Access and Examines Long-term Exposure to Abiraterone AcetateMon, 23 Jan 2012Conditions: Metastatic Castration-resistant Prostate Cancer; Metastatic Breast Cancer
Interventions: Drug: Abiraterone acetate; Drug: Abiraterone acetate
Sponsor: Janssen Research & Development, LLC
Not yet recruiting - verified January 2012 - Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Latin AmericaMon, 23 Jan 2012Condition: Glaucoma
Intervention: Drug: Brinzolamide/Timolol Maleate Fixed Combination (AZARGA)
Sponsor: Alcon Research
Recruiting - verified January 2012 - Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)Mon, 23 Jan 2012Condition: Post-Traumatic Stress Disorder
Interventions: Drug: Tramadol; Drug: Placebo
Sponsors: INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium; U.S. Army Medical Research and Materiel Command
Recruiting - verified January 2012 - A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing LossMon, 23 Jan 2012Condition: Hearing Loss, Sensorineural
Interventions: Drug: PF-04958242; Drug: PF-04958242; Drug: Placebo
Sponsor: Pfizer
Recruiting - verified January 2012 - Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral RegurgitationMon, 23 Jan 2012Condition: Severe Degenerative Mitral Regurgitation
Intervention: Behavioral: mitral valve repair
Sponsors: University of Zurich; Valtech Cardio Ltd
Recruiting - verified January 2012 - A Russian Prospective Observational Study of Invasive Fungal Infections in Patients With Acute Leukemia and Hematopoietic Stem Cell TransplantationMon, 23 Jan 2012Condition: Systemic Mycosis
Intervention:
Sponsor: National Hematological Society, Russia
Not yet recruiting - verified January 2012 - A Mediterranean-style Breakfast and Postprandial Lipid Disorders in Obese Pre-adolescents and AdultsMon, 23 Jan 2012Condition: Obesity
Interventions: Dietary Supplement: Mediterranean-style breakfast; Dietary Supplement: Western-style breakfast
Sponsor: National Research Council, Spain
Recruiting - verified January 2012 - Effect of LEGALON SIL on Hepatitis C Virus Recurrence in Stable Liver Transplanted PatientsMon, 23 Jan 2012Condition: Hepatitis C Virus Recurrence
Interventions: Drug: Silibinin (Legalon-SIL); Drug: Saline
Sponsors: Rottapharm; Azienda Ospedaliera Universitaria Policlinico
Recruiting - verified January 2012 - Effect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.Mon, 23 Jan 2012Conditions: Polycystic Ovary Syndrome; Estro-progestin Drugs
Interventions: Drug: 3 mg drospirenone and 20 µg ethinyl-estradiol; Drug: 3 mg drospirenone and 30 µg ethinyl-estradiol
Sponsor: Catholic University of the Sacred Heart
Completed - verified January 2012
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